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Kei Muro Selected Research

Leucovorin (Folinic Acid)

3/2022Impact of omitting fluorouracil from FOLFIRI plus bevacizumab as second-line chemotherapy for patients with metastatic colorectal cancer.
11/2021Phase I study of napabucasin in combination with FOLFIRI + bevacizumab in Japanese patients with metastatic colorectal cancer.
11/2021Impact of UGT1A1 genotype on the efficacy and safety of irinotecan-based chemotherapy in metastatic colorectal cancer.
11/2021Clinical implications of using both fluoropyrimidine and paclitaxel in patients with severe peritoneal metastasis of gastric cancer: A post hoc study of JCOG1108/WJOG7312G.
4/2021A triplet combination of FOLFOXIRI plus cetuximab as first-line treatment in RAS wild-type, metastatic colorectal cancer: a dose-escalation phase Ib study.
1/2021Proton Pump Inhibitor Use and the Efficacy of Chemotherapy in Metastatic Colorectal Cancer: A Post Hoc Analysis of a Randomized Phase III Trial (AXEPT).
11/2020Phase I Study of Alternate-Day Administration of S-1, Oral Leucovorin, and Bevacizumab for Refractory Metastatic Colorectal Cancer.
9/2020Morphologic response to chemotherapy containing bevacizumab in patients with colorectal liver metastases: A post hoc analysis of the WJOG4407G phase III study.
8/2020Impact of sex and histology on the therapeutic effects of fluoropyrimidines and oxaliplatin plus bevacizumab for patients with metastatic colorectal cancer in the SOFT trial.
1/2020Randomized phase II/III study of 5-fluorouracil/l-leucovorin versus 5-fluorouracil/l-leucovorin plus paclitaxel administered to patients with severe peritoneal metastases of gastric cancer (JCOG1108/WJOG7312G).
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Kei Muro Research Topics

Disease

118Neoplasms (Cancer)
06/2022 - 04/2002
113Colorectal Neoplasms (Colorectal Cancer)
03/2022 - 01/2002
88Stomach Neoplasms (Stomach Cancer)
03/2022 - 12/2003
39Neoplasm Metastasis (Metastasis)
06/2022 - 03/2003
38Adenocarcinoma
10/2022 - 09/2011
28Disease Progression
01/2022 - 05/2009
26Esophageal Neoplasms (Esophageal Cancer)
10/2022 - 06/2003
20Neutropenia
12/2021 - 12/2003
14Esophageal Squamous Cell Carcinoma
10/2022 - 11/2011
11Ascites
02/2021 - 11/2009
9Diarrhea
07/2022 - 05/2011
8Nausea
08/2020 - 01/2011
7Vomiting
08/2020 - 08/2003
6Squamous Cell Carcinoma (Epidermoid Carcinoma)
10/2022 - 12/2016
6Gastrointestinal Neoplasms (Gastrointestinal Cancer)
01/2021 - 12/2003
6Hypertension (High Blood Pressure)
01/2019 - 10/2014
6Fatigue
11/2016 - 08/2003
5Anorexia
01/2022 - 08/2003
5Colonic Neoplasms (Colon Cancer)
01/2021 - 07/2011
5Anemia
01/2019 - 04/2010
5Breast Neoplasms (Breast Cancer)
10/2012 - 05/2002
4Drug-Related Side Effects and Adverse Reactions
01/2022 - 12/2016
4Squamous Cell Carcinoma of Head and Neck
01/2022 - 11/2016
4Microsatellite Instability
06/2021 - 01/2019
4Leukopenia
08/2020 - 08/2011
4Thrombocytopenia (Thrombopenia)
01/2019 - 08/2011
4Infections
01/2019 - 04/2014
3Constipation
01/2022 - 11/2016
3Body Weight (Weight, Body)
01/2022 - 12/2015
3Febrile Neutropenia
12/2021 - 01/2017
3Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
08/2021 - 10/2007
3Interstitial Lung Diseases (Interstitial Lung Disease)
08/2021 - 03/2014
3Pancreatic Neoplasms (Pancreatic Cancer)
12/2019 - 10/2007
3Hepatocellular Carcinoma (Hepatoma)
10/2019 - 04/2014
3Disseminated Intravascular Coagulation
09/2017 - 12/2011
3Carcinoma (Carcinomatosis)
01/2017 - 01/2013
3Jaundice (Icterus)
01/2016 - 07/2011

Drug/Important Bio-Agent (IBA)

47Fluorouracil (Carac)FDA LinkGeneric
03/2022 - 01/2002
44Bevacizumab (Avastin)FDA Link
03/2022 - 04/2009
40Oxaliplatin (Eloxatin)FDA LinkGeneric
03/2022 - 04/2006
40Irinotecan (Camptosar)FDA LinkGeneric
03/2022 - 08/2003
34Leucovorin (Folinic Acid)FDA Link
03/2022 - 01/2002
26Paclitaxel (Taxol)FDA LinkGeneric
07/2022 - 01/2011
26NivolumabIBA
01/2022 - 01/2017
24Cetuximab (Erbitux)FDA Link
06/2022 - 04/2009
23Cisplatin (Platino)FDA LinkGeneric
05/2021 - 01/2009
21Biomarkers (Surrogate Marker)IBA
01/2022 - 06/2012
21RamucirumabIBA
11/2021 - 10/2014
20PlatinumIBA
01/2022 - 01/2009
18pembrolizumabIBA
10/2022 - 06/2016
14Panitumumab (Vectibix)FDA Link
10/2020 - 10/2007
13Capecitabine (Xeloda)FDA Link
12/2021 - 10/2010
12Immune Checkpoint InhibitorsIBA
06/2022 - 09/2016
11Monoclonal AntibodiesIBA
01/2022 - 07/2004
11Trastuzumab (Herceptin)FDA Link
10/2020 - 05/2011
10Pharmaceutical PreparationsIBA
01/2022 - 05/2002
10taxaneIBA
07/2021 - 10/2012
10trifluridine tipiracil drug combinationIBA
04/2021 - 10/2012
9human ERBB2 proteinIBA
03/2022 - 05/2011
9Docetaxel (Taxotere)FDA Link
02/2021 - 11/2010
7ErbB Receptors (EGF Receptor)IBA
04/2021 - 10/2007
7regorafenibIBA
11/2019 - 01/2017
6Proteins (Proteins, Gene)FDA Link
01/2022 - 01/2013
6S-1 plus cisplatinIBA
01/2022 - 11/2010
6BilirubinIBA
10/2019 - 07/2011
5B7-H1 AntigenIBA
10/2022 - 11/2016
5AntibodiesIBA
01/2019 - 01/2017
4Antineoplastic Agents (Antineoplastics)IBA
04/2021 - 01/2008
4Cytotoxins (Cytolysins)IBA
09/2020 - 06/2011
4130-nm albumin-bound paclitaxelIBA
06/2020 - 07/2014
4Taxoids (Taxanes)IBA
04/2020 - 06/2011
4Aspartate Aminotransferases (Aspartate Transaminase)IBA
06/2017 - 12/2016
4XELOXIBA
12/2016 - 10/2010
3Reactive Oxygen Species (Oxygen Radicals)IBA
07/2022 - 11/2021
3napabucasinIBA
07/2022 - 11/2021
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2021 - 02/2012
3gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA
12/2019 - 04/2010
3Circulating Tumor DNAIBA
02/2019 - 12/2016
3Growth Factor ReceptorsIBA
01/2019 - 08/2010
3Alanine Transaminase (SGPT)IBA
01/2019 - 12/2016
3Immunoglobulin G (IgG)IBA
01/2019 - 12/2017
3CreatinineIBA
10/2018 - 01/2017
3Dacarbazine (DIC)FDA LinkGeneric
09/2017 - 12/2011
3Sunitinib (Sutent)FDA Link
04/2014 - 12/2010
3EverolimusFDA Link
11/2013 - 04/2010
3TOR Serine-Threonine KinasesIBA
11/2013 - 04/2010
3TegafurIBA
09/2010 - 12/2003

Therapy/Procedure

151Drug Therapy (Chemotherapy)
10/2022 - 01/2002
82Therapeutics
01/2022 - 12/2003
15Chemoradiotherapy
02/2021 - 06/2003
14Combination Drug Therapy (Combination Chemotherapy)
07/2021 - 11/2009
9Immunotherapy
01/2022 - 01/2017
6Neoadjuvant Therapy
01/2022 - 08/2015
6Radiotherapy
05/2017 - 11/2005
5Adjuvant Chemotherapy
01/2021 - 11/2008
4Aftercare (After-Treatment)
01/2022 - 01/2015
4Drug Tapering
01/2019 - 05/2011
3Gastrectomy
01/2022 - 09/2004
3Intravenous Infusions
01/2022 - 10/2012
3Induction Chemotherapy
02/2021 - 03/2009